Pseudouridine (Ψ) is a C–C glycosidic isomer of uridine (U) with a distinct structure, in which the uracil base is covalently attached to the ribose ring through a C5–C1 linkage, as opposed to the ...
Ten-eleven translocation (TET) family proteins (TETs), specifically, TET1, TET2 and TET3, can modify DNA by oxidizing 5-methylcytosine (5mC) iteratively to yield 5-hydroxymethylcytosine (5hmC), ...
Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...
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