Boston-based PerkinElmer Life and Analytical Sciences has released the prOTOF™ 2000, the first commercially available matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass ...

Nail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.

Collectively, the articles in the December 2017 special issue of SLAS Discovery on Advances in MALDI Mass Spectrometry within Drug Discovery present a snapshot of innovation in the MALDI application ...

MALDI In-Source Decay (ISD) Mass Spectrometry has emerged as a powerful technique for the rapid characterisation of peptides. By utilising matrix-assisted laser desorption/ionisation, the method ...

Perhaps no tool has been as instrumental to the proteomics revolution as the mass spectrometer. With the ability to deconvolute highly complex mixtures over a wide range of abundance levels, these ...

Single-cell MALDI mass spectrometry (MS) imaging resolution is currently limited by the size of laser spot diameter, matrix crystal size/homogeneity, displacement of analytes during matrix deposition, ...

High-throughput screening assays can identify small molecule modulators of biochemical activities and interactions from large libraries of active compounds in drug discovery studies. However, ...

Scientific computing and the ability to write specific programs to analyze large datasets of biological information has become an increasingly important skill with regards to advancing biological ...

Mass spectrometry is a cornerstone technique across various scientific disciplines, enabling precise analysis of complex samples, characterization of atom clusters and molecules, and elucidation of ...