lasma metabolomic analysis in active tuberculosis patients and healthy controls. Cerebral tuberculosis (CTB), a severe and often fatal form of central nervous system (CNS) tuberculosis, poses ...

Mycobacterium tuberculosis infects the respiratory tract and establishes a complex interplay with the host immune system. Upon inhalation, bacilli are phagocytosed by alveolar macrophages but evade ...

Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis, is deadly in part because of ...

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featuring lung ...

Mycobacterium tuberculosis harbours two expansive multigene families, designated PE and PPE, whose members collectively constitute around 10 % of the bacillary coding potential. These proteins are ...

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism—the intrinsic link between metabolism in immune cells ...

A histone acetylome-wide associations study (HAWAS) performed in immune cells from patients with active Mycobacterium tuberculosis infection versus those from healthy controls, has for the first time ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune ...

A more accurate understanding of this pathogenic mechanism could provide a target against the bacterium that caused 1.6 million deaths in 2021, along with 10 million new cases of tuberculosis every ...