Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as ...

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate.

In the eukaryotic secretory and endocytic pathways, transport vesicles shuttle cargo among intracellular organelles and to and from the plasma membrane. Cargo delivery entails fusion of the transport ...

A new imaging approach is shedding light on one of cell biology’s most elusive questions: how lipids are organized and sorted within membranes.