By freezing a crucial phosphoric acid complex to near absolute zero, scientists uncovered a single, unexpectedly stable structure at the heart of proton transport.

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, bending it by 90 degrees to initiate gene copying.

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. They have revealed a unique viral mechanism: A molecular ring anchors the viral copying machine ...

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...

Scientists on their quest to find the origin of life have stared into the primordial soup, trying to answer the ultimate ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

This study addresses an important problem in gene regulation, namely, which features of chromatin regulate potential RNA Polymerase 2 activity at a locus. The authors provided evidence that specific ...

Francis Crick missed a crucial seminar in 1951, probably because he was seeing a lover. James Watson did go, failed to take notes and misremembered key details. As a result, their first model of DNA ...

“The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we conceived of life itself. The X-ray crystallography by Rosalind Franklin ...